Key publications

Hartland H*, Mahdavi K*, Jelen LA, Strawbridge R, Young AH, Alexander L (2023), “A transdiagnostic systematic review and meta-analysis of ketamine’s anxiolytic effects” Journal of Psychopharmacology

Alexander L*, Wood CM*, Gaskin PLR, Sawiak SJ, Fryer TD, Hong YT, McIver L, Clarke HF, Roberts AC (2020), “Over-activation of primate subgenual cingulate cortex enhances the cardiovascular, behavioural and neural responses to threat” Nature Communications 

Alexander L, Gaskin PLR, Sawiak SJ, Fryer TD, Hong YT, Cockcroft GJ, Clarke HF, Roberts AC (2019), “Fractionating Blunted Reward Processing Characteristic of Anhedonia by Over-Activating Primate Subgenual Anterior Cingulate Cortex” Neuron

2023

Wood CM, Alexander L, Alsio J, Santangelo AM, McIver L, Cockcroft GJ, Roberts AC (2023), “Chemogenetics identifies separate area 25 brain circuits involved in anhedonia and anxiety in marmosets” Science Translational Medicine

2022

Strawbridge R*, Alexander L*, Richardson T, Young AH, Cleare AJ (2022) Is there a ‘bipolar iceberg’ in UK primary care psychological therapy services? Psychological Medicine

Alexander L, Wood CM, Roberts AC (2022), “The ventromedial prefrontal cortex and emotion regulation: lost in translation?” The Journal of Physiology

Alexander L, Young AH (2022), “Recent Advances in the Psychopharmacology of Major Depressive Disorder” British Journal of Psychiatry Advances

2021

Alexander L, Jelen LA, Mehta MA, Young AH (2021), “The anterior cingulate cortex as a key locus of ketamine’s antidepressant action” Neuroscience & Biobehavioral Reviews

Alexander L, Banai-Tizkar R, Wood CM, Roberts AC (2021), “Quantifying anhedonia-like symptoms in marmosets using appetitive Pavlovian conditioning” STAR Protocols

2020

Stawicka ZM, Massoudi R, Horst NK, Koda K, Gaskin PLR, Alexander L, Santangelo AM, Cockcroft GJ, Wood CM, Roberts AC (2020), “Ventromedial prefrontal area 14 provides opposing regulation of threat and reward-elicited responses in the common marmoset” PNAS

2019

Alexander L, Clarke HF, Roberts AC (2019), “A Focus on the Functions of Area 25” Brain Sci

Zeredo JL, Quah SKL, Wallis CU, Alexander L, Cockcroft GJ, Santangelo AM, Xia J, Shiba Y, Dalley JW, Cardinal RN, Roberts AC, Clarke HF (2019), “Glutamate within the marmoset anterior hippocampus interacts with area 25 to regulate the behavioral and cardiovascular correlates of high-trait anxiety” J Neurosci

2017

Wallis CU, Cardinal RN, Alexander L, Roberts AC, Clarke HF (2017), “Opposing roles of primate areas 25 and 32 and their putative rodent homologs in the regulation of negative emotion” PNAS