Key publications
Alexander L, Hawkins PCT, Evans JW, Mehta MA, Zarate Jr CA (2023), “Preliminary evidence that ketamine alters anterior cingulate resting-state functional connectivity in depressed individuals” Translational Psychiatry
Alexander L*, Wood CM*, Gaskin PLR, Sawiak SJ, Fryer TD, Hong YT, McIver L, Clarke HF, Roberts AC (2020), “Over-activation of primate subgenual cingulate cortex enhances the cardiovascular, behavioural and neural responses to threat” Nature Communications
Alexander L, Gaskin PLR, Sawiak SJ, Fryer TD, Hong YT, Cockcroft GJ, Clarke HF, Roberts AC (2019), “Fractionating Blunted Reward Processing Characteristic of Anhedonia by Over-Activating Primate Subgenual Anterior Cingulate Cortex” Neuron
2025
Alexander L, Beck K, Bocharova M, Young AH, Stewart R, Carter R, Mueller C (2025), “Late-life affective disorders and risk of progression to dementia: retrospective cohort study of patients in secondary care” British Journal of Psychiatry
Tapoi C, Alexander L, …, Pinto Da Costa M (2025), “Early career psychiatrists’ perceptions of and training experience in electroconvulsive therapy: A cross-sectional survey across Europe” European Psychiatry
2024
Critchley HD, Tracy DK, Mahli GS, Alexander L, …, Young AH (2024) “Academic Psychiatry is everyone’s business” British Journal of Psychiatry
Alexander L*, Anderson D*, Baxter L, Claydon M, Rucker J, Robinson ESJ (2024) “Preclinical models for evaluating psychedelics in the treatment of major depressive disorder” British Journal of Pharmacology
2023
Hartland H*, Mahdavi K*, Jelen LA, Strawbridge R, Young AH, Alexander L (2023) “A transdiagnostic systematic review and meta-analysis of ketamine’s anxiolytic effects” Journal of Psychopharmacology
Wood CM, Alexander L, Alsio J, Santangelo AM, McIver L, Cockcroft GJ, Roberts AC (2023) “Chemogenetics identifies separate area 25 brain circuits involved in anhedonia and anxiety in marmosets” Science Translational Medicine
2022
Strawbridge R*, Alexander L*, Richardson T, Young AH, Cleare AJ (2022) Is there a ‘bipolar iceberg’ in UK primary care psychological therapy services? Psychological Medicine
Alexander L, Wood CM, Roberts AC (2022) “The ventromedial prefrontal cortex and emotion regulation: lost in translation?” The Journal of Physiology
Alexander L, Young AH (2022), “Recent Advances in the Psychopharmacology of Major Depressive Disorder” British Journal of Psychiatry Advances
2021
Alexander L, Jelen LA, Mehta MA, Young AH (2021), “The anterior cingulate cortex as a key locus of ketamine’s antidepressant action” Neuroscience & Biobehavioral Reviews
Alexander L, Banai-Tizkar R, Wood CM, Roberts AC (2021), “Quantifying anhedonia-like symptoms in marmosets using appetitive Pavlovian conditioning” STAR Protocols
2020
Stawicka ZM, Massoudi R, Horst NK, Koda K, Gaskin PLR, Alexander L, Santangelo AM, Cockcroft GJ, Wood CM, Roberts AC (2020), “Ventromedial prefrontal area 14 provides opposing regulation of threat and reward-elicited responses in the common marmoset” PNAS
2019
Alexander L, Clarke HF, Roberts AC (2019), “A Focus on the Functions of Area 25” Brain Sci
Zeredo JL, Quah SKL, Wallis CU, Alexander L, Cockcroft GJ, Santangelo AM, Xia J, Shiba Y, Dalley JW, Cardinal RN, Roberts AC, Clarke HF (2019), “Glutamate within the marmoset anterior hippocampus interacts with area 25 to regulate the behavioral and cardiovascular correlates of high-trait anxiety” J Neurosci
2017
Wallis CU, Cardinal RN, Alexander L, Roberts AC, Clarke HF (2017), “Opposing roles of primate areas 25 and 32 and their putative rodent homologs in the regulation of negative emotion” PNAS